Endotelio Pro

1-MNA is a substance that occurs naturally in the human body. It is formed as a result of the metabolism of niacin. Niacin takes part in the synthesis of the coenzymes NAD⁺ and NADP⁺, which are found in numerous cells and are involved in a range of important processes in the body. As we age, our body’s ability to convert niacin to 1-MNA decreases and the amount of coenzyme NAD⁺ drops as well. This process starts after the age of 30. It has been confirmed that between the ages of 40 and 60, NAD⁺ levels go down by up to 50%. This results in slower cell production and ageing. In young cells and tissues, NAD⁺ levels are higher, which translates into good physical activity and cognitive function as well as greater potential for cell regeneration.

1-MNA can complement a diet that supports the production of SIRT1. This is one of the seven enzymatic proteins—sirtuins—that play a significant role in cellular metabolism and the cell’s response to stress conditions. Their activity is closely dependent on the level of NAD⁺. SIRT1 is mainly located in the cell nucleus and performs several key functions. The most important is to support the cell’s resistance to stress, its ability to survive and the process of differentiation. In young and healthy cells, the level of SIRT1 is high, which allows for better regeneration. A decrease in SIRT1 activity is therefore one of the possible signs of aging. Therefore supporting its production may have a positive impact on our health and vitality.

The richest known natural sources of 1-MNA are Wakame brown algae (Undaria pinnatifida) and green tea leaves (Camellia sinensis). Thanks to our research, we were able to synthesize this valuable substance and demonstrate its safety, obtaining a positive opinion from the European Food Safety Authority (EFSA)* and an authorization for the so-called “novel food.” As a result, we developed the innovative dietary supplement ENDOTELIO.

Recommended daily intake: 1 capsule with food. The capsule should be taken with water.

Warning:

Do not use in case of hypersensitivity to any of the ingredients of the preparation. Do not use in children under 18 years of age or in pregnant or breastfeeding women. Do not exceed the recommended daily dose. A food supplement cannot be used as a substitute for a varied diet. A balanced diet and a healthy lifestyle are important for maintaining good health.