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Ground-breaking scientific discovery

The discovery of 1‑MNA was the result of many years of research at various research sites all over the world. Scientists from Poland, the United States, Germany, Switzerland, Spain, Sweden, Denmark, Japan, China and Iran have conducted hundreds of studies on the 1-MNA molecule.

1-MNA belongs to the group of quaternary pyridinium salts and is formed in the human body as a result of liver metabolism.

1-MNA inhibits the enzyme nicotinamide N-methyltransferase which participates in the synthesis of NAD+. As a result, it optimizes the NAD+ level. NAD+ is a coenzyme found in numerous cells and involved in a range of important processes in the body. Adequate NAD+ levels are beneficial for the proper functioning of cells.

Our cells used NAD+ to function. Thus, its level decline with age. This process can accelerate around age 30.

1-MNA is a new approch to this process.

The molecule is patented (EP 1713480). 1-MNA is an endogenous, vitamin-derived substance, physiologically present within the human body.

1-MNA molecule

1-MNA also occurs in natural sources. It can be found in a few foods present in the diet. The richest known sources of 1-MNA are Wakame brown algae (Undaria pinnatifida) and green tea leaves (Camellia sinensis).

To supply an adequate amount of 1-MNA to the body, approximately 2 kg of Wakame algae or green tea leaves would have to be consumed daily.

1-MNA has been subject to in-depth evaluation by the European Food Safety Authority (EFSA). The results showed that 1-MNA is safe for use.*

* EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), Turck D et all., Scientific Opinion, Safety of 1-methylnicotinamide chloride (1-MNA) as a novel food pursuant to Regulation (EC) No 258/97. EFSA Journal 2017;15(10): 5001.